Pseudotetraivprolides from Pseudomonas entomophila Provide Insights into the Biosynthesis of Detoxin/Rimosamide-Like Anti-Antibiotics

Design of a multienzyme derived from mouse fatty acid synthase for the compartmentalized production of 2-pyrone polyketides

Molecular mechanisms of the mammalian fatty acid cycle

The enzyme kinetics of branched-chain fatty acid synthesis of metazoan fatty acid synthase

Design principles imprinted by evolution

Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases

The Kinetics of Carbon-Carbon Bond Formation in Metazoan Fatty Acid Synthase and Its Impact on Product Fidelity

The malonyl/acetyl-transferase from murine fatty acid synthase is a promiscuous engineering tool for editing polyketide scaffolds

How Acyl Carrier Proteins (ACPs) Direct Fatty Acid and Polyketide Biosynthesis

Docking Domain Engineering in a Modular Polyketide Synthase and Its Impact on Structure and Function

Enzymology of assembly line synthesis by modular polyketide synthases

Chemoenzymatic synthesis of fluorinated polyketides

Solution Structure and Conformational Flexibility of a Polyketide Synthase Module

Impfstoffe für alle? Dodecin als Impfstoffplattform

Cell-Free Synthesis of Natural Compounds from Genomic DNA of Biosynthetic Gene Clusters

Ketosynthase Domain Constrains the Design of Polyketide Synthases

Dodecin as carrier protein for immunizations and bioengineering applications

The role of the iterative modules in polyketide synthase evolution

The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase

Analysis of the co-translational assembly of the fungal fatty acid synthase (FAS)

Type I fatty acid synthase trapped in the octanoyl-bound state

Structure of the archaeal chemotaxis protein CheY in a domain-swapped dimeric conformation

Comparative biochemical and structural analysis of the flavin-binding dodecins from Streptomyces davaonensis and Streptomyces coelicolor reveals striking differences with regard to multimerization

Protein denaturation at the air-water interface and how to prevent it

Fatty Acid Biosynthesis: Chain-Length Regulation and Control

Engineering of Chimeric Polyketide Synthases Using SYNZIP Docking Domains

Probing the modularity of megasynthases by rational engineering of a fatty acid synthase Type I

Site-Specific Labelling of Multidomain Proteins by Amber Codon Suppression

Analysis and engineering of substrate shuttling by the acyl carrier protein (ACP) in fatty acid synthases (FASs)

Engineering strategies for rational polyketide synthase design

An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae

Characterization of the small flavin-binding dodecin in the roseoflavin producer Streptomyces davawensis

Flavin Storage and Sequestration by Mycobacterium tuberculosis Dodecin

Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering

Strategies in megasynthase engineering - fatty acid synthases (FAS) as model proteins

Engineering fungal de novo fatty acid synthesis for short chain fatty acid production

Engineering fatty acid synthases for directed polyketide production

Expanding the product portfolio of fungal type I fatty acid synthases

Crystallization and X-ray diffraction studies of a complete bacterial fatty-acid synthase type I

Cryo-EM structure of fatty acid synthase (FAS) from Rhodosporidium toruloides provides insights into the evolutionary development of fungal FAS

Multi-Ligand-Binding Flavoprotein Dodecin as a Key Element for Reversible Surface Modification in Nano-biotechnology

Modular polyketide synthases (PKSs): a new model fits all? Chembiochem

Perspectives on the evolution, assembly and conformational dynamics of fatty acid synthase type I (FAS I) systems

Directed manipulation of a flavoprotein photocycle

Structure and conformational variability of the mycobacterium tuberculosis fatty acid synthase multienzyme complex

The flavoprotein dodecin as a redox probe for electron transfer through DNA

Ultrafast excited-state deactivation of flavins bound to dodecin

Mechanism of substrate shuttling by the acyl-carrier protein within the fatty acid mega-synthase

Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase

Electrochemical switching of the flavoprotein dodecin at gold surfaces modified by flavin-DNA hybrid linkers

Direct structural insight into the substrate-shuttling mechanism of yeast fatty acid synthase by electron cryomicroscopy

Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase

Blue-light-triggered photorelease of active chemicals captured by the flavoprotein dodecin

Dodecin is the key player in flavin homeostasis of archaea

Inhibition of the fungal fatty acid synthase type I multienzyme complex

Dodecin sequesters FAD in closed conformation from the aqueous solution

Dodecins: a family of lumichrome binding proteins

Parameters affecting the X-ray dose absorbed by macromolecular crystals

Expression, crystallization and crystallographic analysis of DegS, a stress sensor of the bacterial periplasm